798 844
Table 3 – Main characteristics and findings of studies investigating magnetic resonance imaging for the diagnosis of bladder endometriosis
Study
Type Setting MRI
Patients,
n
(%)
Reference
Parameter, % (95% confidence interval)
ACC
type
Total
DIE
BE
standard Sensitivity Specificity
PPV
NPV
LR+
LR
(%)
Kru¨ger 2014
[68]RS
SI
1.5 T
18 18 (100)
18 (100)
S + H NA
NA
NA
NA
NA
NA
NA
Chamie´ 2009
[69]PS
SI
1.5 T
92 77 (83.7)
13 (14.1)
S + H 23.1
(5.0–53.8)
100
(95.4–100)
100
(29.2–100)
88.8
(80.3-94.5)
1
0.77
(0.6-1.0)
89.1
Hottat 2009
[70]
PS
SI
3.0 T
US gel
41 27 (65.9)
2/41
(4.9)
S + H 50.0
(1.3–98.7)
100
(91.0–100)
100
(2.5-100)
97.5
(86.8-99.8)
1
0.50
(0.13-2.0)
97.6
Bazot 2011
[71]RS
SI
1.5 T
IV Gd
158 126 (79.7)
8/158
(5.1)
S + H R
1
: 62.5
(35.0–78.9)
R
2
: 75.0
(50.8–75.0)
R
3
: 87.5
(63.9–87.5)
R
1GD
: 75.0
(48.0–85.0)
R
2GD
: 87.5
(63.9–87.5)
R
3GD
: 87.5
(63.9–87.5)
R
1
: 98.7
(97.2–99.5)
R
2
: 100
(98.7–100)
R
3
: 100
(98.7–100)
R
1GD
: 99.3
(97.9–99.9)
R
2GD
: 100
(98.7–100)
R
3GD
: 100
(98.7–100)
R
1
: 71.4
(40.0–90.2)
R
2
: 100
(67.7–100)
R
3
: 100
(73.0–100)
R
1GD
: 85.7
(54.9–97.1)
R
2GD
: 100
(73.0–100)
R
3GD
: 100
(73.0–100)
R
1
: 98.0
(96.6–98.9)
R
2
: 98.7
(97.4–98.7)
R
3
: 99.3
(98.1–99.3)
R
1GD
: 98.7
(97.2–99.2)
R
2GD
: 99.3
(98.1–99.3)
R
3GD
: 99.3
(98.1–99.3)
R
1
: 46.9
(12.5–173)
R
2
:
1
R
3
:
1
R
1GD
: 112.5
(22.8–638.7)
R
2GD
:
1
R
3GD
:
1
R
1
: 0.38
(0.21–0.67)
R
2
: 0.25
(0.25–0.49)
R
3
: 0.12
(0.12–0.36)
R
1GD
: 0.25
(0.15–0.53)
R
2GD
: 0.12
(0.12–0.36)
R
3GD
: 0.12
(0.12–0.36)
R
1
: 96.8
R
2
: 98.7
R
3
: 99.4
R
1GD
: 98.1
R
2GD
: 99.4
R
3GD
: 99.4
Kru¨ger 2013
[72]RS
SI
1.5 T
152 NA
21 (13.8)
S + H 81.0
(64.2– 97.7)
94.7
(90.8–98.5)
70.8
(52.6–89.0)
96.9
(93.9–99.9)
15.15
(7.16–32.07)
0.20
(0.08–0.49)
92.8
Scardapane
2013
[73]
PS
SI
1.5 T
143 76 (63.9)
3 (2.5)
S + H 66.7
(9.4–99.2)
94.3
(88.6–97.7)
22.2
(2.8–60.0)
99.2
(95.3–100)
11.71
(3.99–34.36)
0.35
(0.07–1.75)
99.2
Di Paola
2015
[74]
RS
SI
1.5 T
115 82 (71.3)
12 (10.4)
S + H 25.0
(5.5–57.2)
100.0
(96.5–100)
100.0
(29.2–100)
92.0
(85.3–96.3)
1
0.75
(0.54–1.04)
92.2
RS = retrospective study; PS = prospective study; SI = single institution; S + H = surgery and histopathology; PPV = positive predictive value; NPV = negative predictive value; LR+ = positive likelihood ratio; LR = negative
likelihood ratio; ACC = accuracy; IV Gd = intravenous gadolinium; NA = not available; R
1
, R
2
, R
3
= reader 1, 2, 3; R
1GD
, R
2GD
, R
3GD
= reader 1, 2, 3 with gadolinium; US: ultrasonography.
E U R O P E A N U R O L O G Y 7 1 ( 2 0 1 7 ) 7 9 0 – 8 0 7
798