796 844
Table 2 – Main characteristics and findings of studies investigating transvaginal ultrasonography for the diagnosis of bladder endometriosis
Study
Type Setting TVS
Patients,
n
(%)
Reference
Parameter, % (95% confidence interval)
ACC
type Total
DIE
BE
standard Sensitivity Specificity
PPV
NPV
LR+
LR
(%)
Bazot 2004
[40]PS
SI
NE
142
79
(55.6)
5 (3.5)
S + H
following
BC
71.4 (NA)
100 (NA)
100 (NA)
98.5 (NA)
NA
NA
98.6
Guerriero
2008
[58]
PS
SI
NE
a88
72
(81.8)
4 (4.5)
S + H
following
BC
100
(40–100)
100
(94–100)
100
100
1
1
100
Hudelist
2011
[41]
PS
3I
NE
155
52
(40.3)
4 (2.6)
S + H
25
100
100
98
75.6
0.75
98
Vimercati
2012
[59]
PS
SI
NE
90
74
(82.2)
6 (6.7)
S + H
66.7
(12.5–98.2)
100
(89.6–100)
100
(19.8–100)
97.7
(86.2–99.9)
1
0.3
97.8
Holland
2013
[60]
PS
SI
NE
198
NA
5 (2.5)
S
100
(48.0–100)
100
(98.1–100)
100
(48.0–100)
100
(98.1–100)
1
1
100
Fratelli
2013
[61]
RS
SI
NE
420
NA
23 (5.5)
S + H
following
BC
61
(39–80)
99
(98–100)
78
(52–94)
98
(96–99)
60.4
(21.6–169)
0.40
(0.24–0.66)
NA
Exacoustos
2014
[62]
PS
3I
NE
104
104
(100)
8 (7.7)
S (all) +H
(some)
100
(63.1–100)
96.9
(91.1–99.4)
72.7
(39.0–94.0)
100
(96.1–100)
32.0
(10.51–97.47)
0 (0)
97.1
Leo´n 2014
[63]
PS
SI
E
51
39
(76.5)
5 (9.8)
S + H
20.0
(0.5–71.6)
100
(92.9–100)
100
(2.5–100)
92.6
(82.1–97.9)
1
0.80
(0.52–1.24)
92.7
Tammaa
2015
[64]
PS
SI
NE
67
NA
4 (6.0)
S
67
(13–100)
97
(92–100)
50
(1.0–99)
98
(95–100)
20.7
(4.3–100)
0.34
(0.01–1.7)
95
RS = retrospective study; PS = prospective study; SI = single institution; 3I = three institutions; NE = nonenhanced; E = enhanced (gel contrast sonovaginography); BE = bladder endometriosis; PPV = positive predictive
value; NPV = negative predictive value; LR+ = positive likelihood ratio; LR = negative likelihood ratio; ACC = accuracy; DIE = deep infiltrating endometriosis; NA = not available; S + H = surgery and histopathology;
BC = Bazot’s criteria; TVS = transvaginal ultrasonography
a
Tenderness-guided.
E U R O P E A N U R O L O G Y 7 1 ( 2 0 1 7 ) 7 9 0 – 8 0 7
796