

CONTENTS
e u r o p e a n u r o l o g y , vo l . 7 1 , n o . 5 , Ma y 2 0 1 7
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The
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http://dx.doi.org/10.1016/j.eururo.2017.03.002693
Salvage Lymph Node Dissection for Node-only Recurrence of Prostate Cancer: Ready for Prime Time?N. Suardi, A. Briganti, G. Gandaglia, N. Fossati, F. Montorsi
Several studies show that salvage lymph-node dissection for node-only recurrence
of prostate cancer after radical treatment might represent a viable treatment
modality for node-only recurrent PCa. However, as long as high quality data is not
available, this approach should still be considered experimental.
695
Adjuvant Treatment of High-risk Renal Cell Carcinoma: Leaving the Desert?N. Kroeger, A. Stenzl, M. Burchardt, J. Bedke
In a recent trial, adjuvant treatment with sunitinib significantly prolonged disease-
free survival compared to placebo. This positive result is muted by the rate of side
effects and overtreatment, raising the question of proper patient and agent selection
in the adjuvant setting.
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Prevalence and Prognostic Significance of PTEN Loss in African-American and European-American Men Undergoing Radical ProstatectomyJ.J. Tosoian, F. Almutairi, C.L. Morais, S. Glavaris, J. Hicks, D. Sundi, E. Humphreys, M. Han,
A.M. De Marzo, A.E. Ross, S.A. Tomlins, E.M. Schaeffer, B.J. Trock, T.L. Lotan
PTEN and ERG alterations in prostate cancer are less likely among African-American
than European-American men. However, PTEN loss remains associated with poor
prostate cancer outcomes in African-American men.
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The Incremental Role of Magnetic Resonance Imaging for Prostate Cancer Staging before Radical ProstatectomyA. Morlacco, V. Sharma, B.R. Viers, L.J. Rangel, R.E. Carlson, A.T. Froemming, R.J. Karnes
We analyzed the added benefit of preoperative magnetic resonance imaging over
clinically-based models alone (Partin Table and Cancer of the Prostate Risk
Assessment score) in the prediction of histological outcomes using multivariable
models and receiver operating characteristic/area under the curve. We found that
preoperative magnetic resonance imaging can improve the prediction of
extracapsular extension and seminal vesical invasion, potentially influencing
treatment choices.
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The CAPRA Score at 10 Years: Contemporary Perspectives and Analysis of Supporting StudiesJ.S. Brajtbord, M.S. Leapman, M.R. Cooperberg
We addressed the development of the University of California San Francisco Cancer
of the Prostate Risk Assessment (CAPRA) score, its methodology, and its supporting
studies. The CAPRA score and similarly designed tools have yielded strong
performance in the prediction of numerous prostate cancer end points.
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