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bladder wall is caused by external peritoneal infiltration

( Fig. 1

). As rightly assessed by the authors, transurethral

resection surgery is ineffective

[1]

. Proper completion of

partial cystectomy need to consider uterine involvement by

external endometriosis which is a quasi-constant compo-

nent of the lesion

( Fig. 1

) and has to be treated without

impairing uterine function; second, intrinsic ureteral

endometriosis due to contiguous extension of bladder

disease requires a resection-reimplantation procedure, but

fortunately this situation is rare. Extrinsic ureteral disease,

often due to remote associated lesions (posterior and/or

lateral), is mainly treated using conservative surgery of the

ureter. In symptomatic bladder disease surgery can be

envisaged in several ways. The first is complete surgery: a

bladder phase, and completed at the same time—or not—via

resection of posterior or lateral lesions, which are always

associated

[5] .

The alternative strategy, called

site-specific

surgery

, is to perform only the anterior procedure and not to

treat posterior lesions when they are important or require

difficult procedures, for example when the disease involves

the digestive tract. Again, preoperative imaging is essential

for a comprehensive description of the lesions, which will

govern the surgery type and principle.

The management plan must be conceived as a

comprehensive and long-term strategy that considers

fertility and childbearing; the excellent review by

Maggiore et al

[1]

provides much useful information for

reflection, but few clear-cut guidelines. Endometriosis

surgery represents a risk to the uterus and adnexa, and

complications of surgery are also a cause of infertility.

Thus, the benefit-to-risk ratio for surgery versus medical

treatment should be carefully considered. One of the main

characteristics of symptoms related to DIE lesions is that

they dramatically respond to therapeutic amenorrhea

[6]

. Therapeutic amenorrhea is one of the key approaches

for treatment of endometriosis in general, and bladder

endometriosis in particular. It can be achieved simply via

continuous administration of combined hormonal contra-

ceptives. Infertility, which may be closely related to

endometriosis, including bladder endometriosis, can be

properly treated via assisted reproductive techniques,

thus bypassing the need for surgery

[1]

.

[(Fig._1)TD$FIG]

Fig. 1 – Extensive bladder endometriosis with detrusor and mucosal involvement and associated uterine infiltration.

E U R O P E A N U R O L O G Y 7 1 ( 2 0 1 7 ) 8 0 8 – 8 1 0

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